NHS Greater Glasgow & Clyde Area Drug and Therapeutics Committee
Greater Glasgow and Clyde Medicines
Medicines Update

Direct Oral Anticoagulants

A new Medicines Update Extra bulletin has been published regarding the use of direct oral anticoagulants (DOACs). This replaces the previous ‘New oral anticoagulant (NOAC) Prescribing in Patients with Non-Valvular Atrial Fibrillation (AF) FAQ’ which was published in 2015. Since publication there have been a number of developments including the additional licensed indication for venous thromboembolism (VTE) and the availability of edoxaban. 


The updated FAQ includes the following key changes:

  • NOACs are now referred to as DOACs
  • the bulletin has been extended to cover AF and VTE indications
  • information is provided regarding the newer agent edoxaban
  • new guidance on what weight to use to calculate renal function with reference to the new Creatinine Clearance calculator on StaffNet or via the GGC Medicines App
  • information added regarding reversal agents
  • additional clinical scenarios



Published 21/02/2017