NHS Greater Glasgow & Clyde Area Drug and Therapeutics Committee
Greater Glasgow and Clyde Medicines
Medicines Update Acute

Apixaban: DOAC of choice for Deep Vein Thrombosis (DVT)/Pulmonary Embolism (PE)

NHSGGC guidance recommends either a DOAC (Direct Oral Anticoagulant) or warfarin for the treatment or secondary prevention of DVT/PE in adult patients.  If a DOAC is desirable, then apixaban is the preferred choice (see StaffNet guideline for prescribing advice).

An initial 21 days of apixaban treatment will be supplied by the hospital pharmacy along with an ‘Apixaban Patient Alert Card’.  The GP will be asked to prescribe the remainder of the course; to facilitate this, the hospital  prescriber should complete an  ‘Apixaban Treatment Discharge Letter’ (see appendix of StaffNet apixaban guideline). 

Please note:  Apixaban is on the NHSGGC Formulary Preferred List but other DOACs (dabigatran, edoxaban and rivaroxaban) are on the Total Formulary and can be prescribed if apixaban is unsuitable for an individual patient; click here for prescribing notes.